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Search Results for " gram-negative bacteria "

218

抑制剂 & 化合物

62

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Cat. No.	Product Name	Target	Signaling Pathways
T14391	Azidamfenicol	Antibacterial; Antibiotic	Microbiology/Virology
	Azidamfenicol 抑制核糖体肽基转移酶，Ki 为 22 µM。Azidamfenicol 是一种广谱氯霉素类抗生素。
T4998L	Cefpodoxime (free acid)	Others	Others
	Cefpodoxime (free acid) 是一种口服的第三代头孢菌素抗生素。除铜绿假单胞菌、肠球菌和脆弱拟杆菌外，它对大多数革兰氏阳性和革兰氏阴性微生物均有效。
T9680	Irloxacin	Antibacterial	Microbiology/Virology
	Irloxacin 是一种口服活性的喹诺酮类抗菌剂，在酸性条件下具有更强大的活性。在体外，Irloxacin 对革兰氏阳性菌和革兰氏阴性菌都具有良好的抗菌谱。
T1008	Cephalexin 头孢氨苄,Cefalexin,Cephacillin	Antibacterial; Antibiotic	Microbiology/Virology
	Cephalexin (Cephacillin) 是一种强口服活性的头孢菌素抗生素。它通过破坏细菌细胞壁的生长来杀死革兰氏阳性和一些革兰氏阴性细菌。它可研究肺炎、链球菌性咽喉炎、细菌性心内膜炎等。
T20525	Chloramphenicol palmitate	Antibacterial; Antibiotic	Microbiology/Virology
	Chloramphenicol palmitate 是一种广谱抗生素，对革兰氏阳性和革兰氏阴性细菌具有活性。 Chloramphenicol palmitate 可用于在含有氯霉素抗性基因的转化细胞中作为细菌选择剂的研究。
T19858	Brodimoprim	DHFR; Antibacterial	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Brodimoprim 是甲氧苄啶的一种类似物，是口服有效的二氢叶酸还原酶抑制剂，对广谱革兰氏阴性和革兰氏阳性细菌具有高度的抑制作用。
T5006	Flucloxacillin sodium 氟氯西林钠,floxacillin sodium	Antibacterial; Antibiotic	Microbiology/Virology
	Flucloxacillin sodium (floxacillin sodium) 是一种高活性抗生素，抑制革兰氏阳性和革兰氏阴性菌。
T6582	Mezlocillin Sodium 美洛西林钠,Baycipen	Antibacterial; Antibiotic	Microbiology/Virology
	Mezlocillin Sodium (Baycipen) 是一种青霉素 β-内酰胺类抗生素，用于治疗由易感染微生物引起的细菌感染。
T3117	Marbofloxacin 马波沙星,Marbofloxacine,Zeniquin,Marbocyl	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Marbofloxacin (Zeniquin) 是一种具有口服活性的氟喹诺酮类广谱抗菌剂。它可研究革兰氏阳性和革兰氏阴性细菌以及支原体引起的感染。
TP1444	Magainin 2 蛙皮素 2	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Magainin 2是从非洲爪蟾皮肤中分离得到的一种抗菌肽。它对许多革兰氏阴性和革兰氏阳性细菌显示出抗生素活性，对原生动物也有活性。它通过优先与细菌膜中丰富的阴离子磷脂相互作用而发挥细胞毒性作用。
T0116	Balofloxacin	DNA gyrase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素，可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成，对革兰氏阴性，革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道，肠道和泌尿道感染。
T0396	Pipemidic acid 吡哌酸,Acido pipemidico	Antibacterial; Antibiotic	Microbiology/Virology
	Pipemidic acid (Acido pipemidico) 是一种新型抗菌剂，对革兰氏阴性菌和某些革兰氏阳性细菌具有活性，可研究肠道、泌尿和胆道感染。
T9066	Merafloxacin CI 934	SARS-CoV	Microbiology/Virology
	Merafloxacin (CI 934) 是一种氟喹诺酮类抗菌药物，也被确定为 SARS-CoV-2 的 1 PRF 抑制剂。它对革兰氏阳性菌和革兰氏阴性菌具有体外活性。
T0274	Cinoxacin 西诺沙星,Compound 64716	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Cinoxacin (Compound 64716) 是一种喹诺酮类的合成抗生素, 与Oxolinic acid 和 Nalidixic acid 活性相似。
T7865	Danofloxacin 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine	Others; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Danofloxacin (Danofloxacin free base) free base 是一种具有口服活性第三代氟喹诺酮抗菌剂，对大多数革兰氏阴性和革兰氏阳性细菌，支原体和衣原体物种具有广谱的活性，并通过抑制细菌的 DNA 回转酶发挥抗菌作用。它可用于牛，猪和鸡呼吸道疾病的研究。
T0133	Cefdinir FK-482,头孢地尼,CI-983,PD 134393	Glutathione Peroxidase; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology
	Cefdinir (FK-482) 是头孢菌素类中的一种半合成广谱抗生素，对几种革兰氏阴性和革兰氏阳性细菌引起的感染有效。它可研究耳，鼻窦，喉咙和皮肤的常见细菌感染。
T83705	BING TFA Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria
	BING是一种来源于日本稻田鱼(O. laptipes)的抗菌肽，由液泡蛋白质分选相关蛋白13D样(Vps13D)衍生而来。对包括耐甲氧西林的金黄色葡萄球菌(MRSA; MICs = 4-64 µg/ml)在内的各种革兰氏阴性和革兰氏阳性细菌都有活性。与氨苄西林、阿莫西林和新霉素共同使用时，对抗铜绿假单胞菌(P. aeruginosa)表现出协同效应，并能抑制大肠杆菌(E. coli)对卡那霉素和氨苄西林的抗药性发展。在体内，BING提高了被鳗弧菌(E. tarda)感染的O. laptipes的生存率。
T73997	Anti gram-positive/negative bacteria agent 1
	Anti gram-positive/negative bacteria agent 1 是一种含有基于MECAM的人工铁载体的抗生素化合物。
T20774	Sarafloxacin A-56620,A 56620,A56620,沙拉沙星	Antibacterial; Antibiotic	Microbiology/Virology
	Sarafloxacin (A56620) 对革兰氏阳性菌和革兰氏阴性菌具有抗菌活性。
T1640	Ciprofloxacin Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Ciprofloxacin (Bay-09867) 是一种有高抗菌活性的氟喹诺酮类抗生素。
T11315	Fosmidomycin sodium salt FR-31564 sodium salt	Antibiotic; Parasite	Microbiology/Virology
	Fosmidomycin sodium salt (FR-31564 sodium salt) 是一种抗感染类抗生素，具有抗疟疾活性，抑制革兰氏阴性菌和革兰氏阳性菌。
T0425	Pefloxacin Mesylate Pefloxacinium mesylate,甲磺酸培氟沙星	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Pefloxacin Mesylate (Pefloxacinium mesylate) 是一种抗菌化合物，可抑制DNA 旋转酶阻断DNA 复制。
T6706	Ticarcillin sodium Ticarpen hydrate,Aerugipen hydrate,替卡西林单钠盐单水合物,BRL 2288,AB 2288,Monapen	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Ticarcillin sodium (Aerugipen hydrate) 主要用于抗革兰氏阴性菌, 也能用于研究嗜麦芽感染。
TP1763L	Magainin 1 acetate	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Magainin 1 acetate 是一种抗菌肽。它对许多革兰氏阴性和革兰氏阳性细菌表现出抗生素活性。
T73054	Moiramide B	Acetyl-CoA Carboxylase; Antibiotic	Metabolism; Microbiology/Virology
	Moiramide B 是一种高效的乙酰辅酶 A 羧化酶 (ACC) 抑制剂（IC50:6 nM),具有抗菌活性，强烈抑制革兰氏阳性菌，但对革兰氏阴性菌的抑制效果较弱。
T19925	EcDsbB-IN-9	Others	Others
	EcDsbB-IN-9 是一种特异性 EcDsbB 抑制剂，靶向革兰氏阴性菌的二硫键形成酶 DsbB。
T16789	Rosoxacin 罗索沙星,Acrosoxacin	Antibacterial; Antibiotic	Microbiology/Virology
	Rosoxacin (Acrosoxacin) 是具有口服活性的喹诺酮类抗生素，具有广谱的抗菌活性，抑制革兰氏阴性菌，包括淋病奈瑟氏球菌(MIC90=0.03 mg/ml)。它在尿路感染中有应用的潜能。
TP1663L	CysHHC10 acetate CysHHC10 acetate(1408311-03-4 free base)	Antibacterial	Microbiology/Virology
	CysHHC10 acetate 对革兰氏阳性菌和革兰氏阴性菌均具有抗菌活性，对大肠杆菌、铜绿假单胞菌、金黄色葡萄球菌和表皮葡萄球菌的 MIC 分别为 10.1、20.2、2.5 和 1.3 mM。
T28229	Olanexidine hydrochloride OPB2045,OPB-2045,OPB-2045 HCl,OPB 2045	Antibacterial	Microbiology/Virology
	Olanexidine hydrochloride (OPB-2045 HCl) 对革兰氏阳性菌和革兰氏阴性菌具有杀菌活性。 Olanexidine hydrochloride 破坏金黄色葡萄球菌的膜完整性。
T17021	Tebipenem LJC 11036	Antibiotic	Microbiology/Virology
	Tebipenem 是一种口服碳青霉烯类抗生素。它对革兰氏阳性和阴性细菌具有广谱活性。
T0897	Nitrofurazone NFZ,呋喃西林,Nitrofural,Furacilin	Dehydrogenase; Antibacterial; Glutathione reductase; Antibiotic	Metabolism; Microbiology/Virology; oxidation-reduction
	Nitrofurazone (Furacilin) 是一种抗生素。
T19860	Clavulanic Acid BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151	Antibacterial; Antifungal	Microbiology/Virology
	Clavulanic Acid(RX-10100) 是一种由生物体克拉维链霉菌产生的主要β-内酰胺类抗生素，是一种强效的细菌 β-内酰胺酶抑制剂，用于研究细菌引起的感染。Clavulanic Acid 具有广谱的生物活性，对多种革兰氏阳性和革兰氏阴性细菌均有活性。
T15947	MAC13243 HCl	Antibacterial	Microbiology/Virology
	MAC13243 HCl 是一种将脂蛋白从内膜运输到外膜的周质伴侣LolA的抑制剂，是一种具有特异性的抗菌剂，对革兰氏阴性菌抑制作用显著。
T19709	Nitrocefin	Others	Others
	Nitrocefin 是 β-内酰胺酶的显色底物，当 β-内酰胺酶将 β-内酰胺环中的酰胺键水解后，Nitrocefin 的颜色会由黄色变为红色。它可用于 β-内酰胺酶耐药抗生素的研究。
T12992	SPR741 acetate SPR741 acetate,NAB741 acetate,SPR741 acetate (1179330-52-9 free base)	Antibacterial	Microbiology/Virology
	SPR741 acetate 是衍生自多粘菌素 B 的阳离子肽，通过增加革兰氏阴性细菌外膜的通透性来抑制严重的革兰氏阴性细菌感从而展现出对革兰氏阴性菌的抗菌活性。SPR741 acetate 常与抗生素联合使用来治疗一些疾病。
T0880	Bronopol 布波尔,BNPK,溴硝醇,BNPD	Antibacterial	Microbiology/Virology
	Bronopol (BNPD) 是一种抗菌剂，对哺乳动物毒性低和对革兰氏阴性菌活性高。
T7043	Cefotetan 头孢替坦,Apacef	Antibacterial; Antibiotic	Microbiology/Virology
	Cefotetan (Apacef) 是一种半合成的头霉素抗生素，能抑制细胞壁合成发挥杀菌作用。
T0788L	Spectinomycin dihydrochloride pentahydrate 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride pentahydrate (Spectogard) 是一种广谱氨基环糊精抗生素，可以抑制多种革兰氏阳性和革兰氏阴性生物的生长。
T1492	Gemifloxacin mesylate LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate	DNA gyrase; Topoisomerase; Antibacterial	DNA Damage/DNA Repair; Microbiology/Virology
	Gemifloxacin mesylate (Gemifloxacin mesylate) 是一种喹诺酮类口服广谱抗菌剂，可研究轻中度肺炎和慢性支气管炎的急性细菌性发作。
T68137	Sanfetrinem GV104326	Antibiotic	Microbiology/Virology
	Sanfetrinem (GV104326) sodium 是一种新型可口服 β-内酰胺酶抗生素，对革兰氏阳性菌和革兰氏阴性菌显示出显著的抗菌活性，可用于研究细菌感染。
T3263	(6R,7S)-Cefminox sodium heptahydrate Meicelin,头孢米诺钠,Cefminox Sodium,Alteporina,Tencef	Antibiotic	Microbiology/Virology
	(6R,7S)-Cefminox sodium heptahydrate (Meicelin) 是一种 Cefminox sodium heptahydrate 的异构体。它也是一种具有广谱抗菌活性的 β-内酰胺头孢菌素抗生素。
T22391	Omeprazole Sodium	P450; Proton pump; Antibacterial; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Omeprazole 是有效的质子泵抑制剂，在胃肠道疾病的研究中具有价值。它竞争性抑制CYP2C19活性，Ki 为 2 到 6 μM。它还抑制革兰氏阴性菌和革兰氏阳性菌生长。它是中性鞘磷脂酶的外泌体抑制剂。
T14951	Chlorhexidine digluconate	Apoptosis; Antibiotic	Apoptosis; Microbiology/Virology
	Chlorhexidine digluconate 是一种广谱防腐剂和消毒剂，具有广谱抗菌活性，抑制革兰氏阳性菌和革兰氏阴性菌，可诱导细胞坏死和凋亡，可用于研究细菌感染。
T4998	Cefpodoxime proxetil	Antibacterial; Antibiotic	Microbiology/Virology
	Cefpodoxime Proxetil 是一种口服的广谱型抗生素。它与青霉素结合蛋白结合，抑制肽聚糖的合成，干扰细菌细胞壁的生物合成。
T9449	Nitrofural [(E)-(5-nitrofuran-2-yl)methylideneamino,(E)-2-((5-硝基呋喃-2-基)亚甲基)肼甲酰胺	Antibacterial	Microbiology/Virology
	Nitrofural 是 20 世纪已在临床应用中确立的硝基呋喃。 Nitrofural 在临床上对广泛的革兰氏阳性和革兰氏阴性细菌（包括许多常见的泌尿道病原体菌株）仍然有效。
T0932	Cefixime FK-027,头孢克肟,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635	Antibacterial; Antibiotic	Microbiology/Virology
	Cefixime (FR-17027) 是一种头孢菌素类抗生素, 可研究一些细菌感染。
T0195	Secnidazole RP-14539,PM-185184,塞克硝唑	Antibiotic; Parasite	Microbiology/Virology
	Secnidazole (PM-185184) 是一种具有口服活性唑类抗生素，半衰期比甲硝唑更长。它有潜力研究细菌性阴道病。
T1060	Flumequine Flumigal,氟甲喹,R-802	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Flumequine (R-802) 是一种喹诺酮类抗生素，对革兰氏阳性菌和革兰氏阴性菌均有效。它是拓扑异构酶 II 抑制剂，抑制细胞分裂，IC50值为 15 μM (3.92 μg/mL)。
T7858	Ceftezole sodium Celoslin,Falomesin,头孢替唑钠,Alomen	Anti-infection; Antibacterial; Antibiotic; Glucosidase	Metabolism; Microbiology/Virology
	Ceftezole sodium (Falomesin) 是一种广谱 cephem 抗生素，具有抑制多种革兰氏阳性菌和革兰氏阴性菌活性。它是一种α-葡萄糖苷酶抑制剂，具有体内抗糖尿病活性。
T21369	Mecillinam Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX	Antibacterial	Microbiology/Virology
	Mecillinam (Hexacillin) 是一种有抗革兰氏阴性菌活性的 β 内酰胺类广谱抗生素。

化合物

Cat.No: T14391

Target: Antibacterial, Antibiotic

Cefpodoxime (free acid)

Cat.No: T4998L

Target: Others

Cat.No: T9680

Target: Antibacterial

Cat.No: T1008

Synonym: 头孢氨苄,Cefalexin,Cephacillin

Target: Antibacterial, Antibiotic

Chloramphenicol palmitate

Cat.No: T20525

Target: Antibacterial, Antibiotic

Cat.No: T19858

Target: DHFR, Antibacterial

Flucloxacillin sodium

Cat.No: T5006

Synonym: 氟氯西林钠,floxacillin sodium

Target: Antibacterial, Antibiotic

Mezlocillin Sodium

Cat.No: T6582

Synonym: 美洛西林钠,Baycipen

Target: Antibacterial, Antibiotic

Cat.No: T3117

Synonym: 马波沙星,Marbofloxacine,Zeniquin,Marbocyl

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: TP1444

Synonym: 蛙皮素 2

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T0116

Target: DNA gyrase, Antibacterial, Antibiotic

Cat.No: T0396

Synonym: 吡哌酸,Acido pipemidico

Target: Antibacterial, Antibiotic

Cat.No: T9066

Synonym: CI 934

Target: SARS-CoV

Cat.No: T0274

Synonym: 西诺沙星,Compound 64716

Target: Topoisomerase, Antibacterial, Antibiotic

Cat.No: T7865

Synonym: 达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine

Target: Others, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T0133

Synonym: FK-482,头孢地尼,CI-983,PD 134393

Target: Glutathione Peroxidase, Antibacterial, Antibiotic

Cat.No: T83705

Synonym: Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria

Anti gram-positive/negative bacteria agent 1

Cat.No: T73997

Cat.No: T20774

Synonym: A-56620,A 56620,A56620,沙拉沙星

Target: Antibacterial, Antibiotic

Cat.No: T1640

Synonym: Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867

Target: Topoisomerase, Antibacterial, Antibiotic

Fosmidomycin sodium salt

Cat.No: T11315

Synonym: FR-31564 sodium salt

Target: Antibiotic, Parasite

Pefloxacin Mesylate

Cat.No: T0425

Synonym: Pefloxacinium mesylate,甲磺酸培氟沙星

Target: Topoisomerase, Antibacterial, Antibiotic

Ticarcillin sodium

Cat.No: T6706

Synonym: Ticarpen hydrate,Aerugipen hydrate,替卡西林单钠盐单水合物,BRL 2288,AB 2288,Monapen

Target: Others, Antibacterial, Antibiotic

Magainin 1 acetate

Cat.No: TP1763L

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T73054

Target: Acetyl-CoA Carboxylase, Antibiotic

Cat.No: T19925

Target: Others

Cat.No: T16789

Synonym: 罗索沙星,Acrosoxacin

Target: Antibacterial, Antibiotic

CysHHC10 acetate

Cat.No: TP1663L

Synonym: CysHHC10 acetate(1408311-03-4 free base)

Target: Antibacterial

Olanexidine hydrochloride

Cat.No: T28229

Synonym: OPB2045,OPB-2045,OPB-2045 HCl,OPB 2045

Target: Antibacterial

Cat.No: T17021

Synonym: LJC 11036

Target: Antibiotic

Cat.No: T0897

Synonym: NFZ,呋喃西林,Nitrofural,Furacilin

Target: Dehydrogenase, Antibacterial, Glutathione reductase, Antibiotic

Clavulanic Acid

Cat.No: T19860

Synonym: BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151

Target: Antibacterial, Antifungal

Cat.No: T15947

Target: Antibacterial

Cat.No: T19709

Target: Others

Cat.No: T12992

Synonym: SPR741 acetate,NAB741 acetate,SPR741 acetate (1179330-52-9 free base)

Target: Antibacterial

Cat.No: T0880

Synonym: 布波尔,BNPK,溴硝醇,BNPD

Target: Antibacterial

Cat.No: T7043

Synonym: 头孢替坦,Apacef

Target: Antibacterial, Antibiotic

Spectinomycin dihydrochloride pentahydrate

Cat.No: T0788L

Synonym: 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate

Target: ribosome, Antibacterial, Antibiotic

Gemifloxacin mesylate

Cat.No: T1492

Synonym: LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate

Target: DNA gyrase, Topoisomerase, Antibacterial

Cat.No: T68137

Synonym: GV104326

Target: Antibiotic

(6R,7S)-Cefminox sodium heptahydrate

Cat.No: T3263

Synonym: Meicelin,头孢米诺钠,Cefminox Sodium,Alteporina,Tencef

Target: Antibiotic

Omeprazole Sodium

Cat.No: T22391

Target: P450, Proton pump, Antibacterial, Autophagy

Chlorhexidine digluconate

Cat.No: T14951

Target: Apoptosis, Antibiotic

Cefpodoxime proxetil

Cat.No: T4998

Target: Antibacterial, Antibiotic

Cat.No: T9449

Synonym: [(E)-(5-nitrofuran-2-yl)methylideneamino,(E)-2-((5-硝基呋喃-2-基)亚甲基)肼甲酰胺

Target: Antibacterial

Cat.No: T0932

Synonym: FK-027,头孢克肟,Cefspan,Cefiximum,Cephoral,FR-17027,CL-284635

Target: Antibacterial, Antibiotic

Cat.No: T0195

Synonym: RP-14539,PM-185184,塞克硝唑

Target: Antibiotic, Parasite

Cat.No: T1060

Synonym: Flumigal,氟甲喹,R-802

Target: Topoisomerase, Antibacterial, Antibiotic

Ceftezole sodium

Cat.No: T7858

Synonym: Celoslin,Falomesin,头孢替唑钠,Alomen

Target: Anti-infection, Antibacterial, Antibiotic, Glucosidase

Cat.No: T21369

Synonym: Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX

Target: Antibacterial

Cat. No.	Product Name	Target	Signaling Pathways
T2P2937	Nonacosane	Others; Antibacterial	Microbiology/Virology; Others
	Nonacosane 是从Baphia massaiensis 分离的，是一种由 29 个碳原子组成的直链烷烃，具有植物代谢物和挥发油成分的作用。
T8160	EGCG Octaacetate 乙酰化表没食子儿茶素没食子酸酯,乙酰化EGCG	Others; Antibacterial	Microbiology/Virology; Others
	EGCG Octaacetate 是表没食子儿茶素没食子酸酯的前药，对革兰氏阳性菌和革兰氏阴性菌有潜在抗菌可能。它可下调 PI3K/Akt/NFκB 磷酸化和 p65 乙酰化来降低促炎介质水平，减少小鼠结肠炎引起的结肠癌。
TN2011	Ombuoside 商陆素-3BETA-芸香糖苷,Ombuin-3beta-rutinoside	Antibacterial	Microbiology/Virology
	Ombuoside (Ombuin-3beta-rutinoside) 是一种从绞股蓝分离得到的糖苷复合物。它具有抗真菌和抗氧化作用。
TQ0251	(Z)-2-decenoic acid (Z)-dec-2-enoic acid,(Z)-2-癸烯酸,cis-2-Decenoic acid,cis-dec-2-enoic acid	Others	Others
	(Z)-2-decenoic acid (cis-dec-2-enoic acid) 是一种由铜绿假单胞菌产生的不饱和脂肪酸。它能够诱导一系列革兰氏阴性细菌(包括铜绿假单胞菌)和革兰氏阳性细菌形成的生物膜发生分散反应。它能够抑制生物膜发育。
T8247	(+)-Aromadendrene	Anti-infection	Microbiology/Virology
	(+)-Aromadendrene 是一种天然产物，对革兰氏阳性菌和革兰氏阴性菌具有显着的抗菌活性。
T8062	Cefazedone Refosporen,头孢西酮	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Cefazedone (Refosporen) 是一种具有抗革兰氏阳性和革兰氏阴性菌活性的时间依赖性头孢菌素抗生素。
T1306	Norfloxacin 氟哌酸,MK-0366,诺氟沙星	DNA gyrase; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Norfloxacin (MK-0366) 是广谱抗生素，能通过结合DNA 旋转酶抑制革兰氏阳性和阴性菌。
T5037	Midecamycin Antibiotic SF-837,Turimycin P3,Medecamycin A1,Rubimycin,麦迪霉素,Platenomycin B1,Espinomycin A	Antibacterial; Antibiotic	Microbiology/Virology
	Midecamycin (Medecamycin A1) 是乙酰氧基取代的大环内酯类抗生素，对革兰氏阳性和阴性菌有效。
T0788	Spectinomycin dihydrochloride 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride (Actinospectacin) 是一种能与细菌核糖体的30S 亚基结合，干扰蛋白质合成的抗生素。
T1679	Thiostrepton Thiactin,Bryamycin,Alaninamide,硫链丝菌素	DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Thiostrepton (Alaninamide) 是一种选择性抑制FOXM1的抗生素。FOXM1会与 YAP/TEAD 复合物结合，形成YAP/TEAD/FOXM1 复合物。
T8302	Ceftiofur	Antibacterial; Antibiotic	Microbiology/Virology
	Ceftiofur 是一种半合成抗生素，对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。
T0814L	Ampicillin Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,氨苄青霉素,Ampicillin acid	Antibacterial; Antibiotic	Microbiology/Virology
	Ampicillin (Aminobenzylpenicillin) 属于 β-内酰胺类抗生素，是一种半合成的青霉素。Ampicillin 具有杀菌活性，对各种革兰氏阳性细菌和革兰氏阴性细菌均有抑制活性。
T5S0814	Berberine hydrogen sulphate Berberine Bisulfate,硫酸氢黄连素,Umbellatine Sulfate	Antibacterial	Microbiology/Virology
	Berberine hydrogen sulphate (Umbellatine Sulfate) 是一种从几种植物中提取的生物碱，对多种微生物具有抗菌活性，包括革兰氏阳性和革兰氏阴性细菌、真菌和原生动物。
T5274	D-(+)-Phenyllactic acid D-3-苯乳酸,D-3-Phenyllactic acid	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-(+)-Phenyllactic acid (D-3-Phenyllactic acid) 是一种由白地霉分泌得到的抗菌剂，可抑制部分来自人类和食品的革兰氏阳性菌以及来自人类的革兰氏阴性菌。
T8262	Fosfomycin sodium Fosfomycin Disodium,磷霉素钠	Antibacterial; Antibiotic	Microbiology/Virology
	Fosfomycin sodium 是一种能透过血脑屏障的广谱抗生素，不可逆地抑制细胞壁合成的早期阶段。它对多种细菌具有杀菌活性，包括耐多药、广泛耐药和耐全药的细菌。
T8148	Mupirocin calcium hydrate 莫匹罗星钙,Mupirocin calcium	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Mupirocin calcium hydrate 是从Pseudomonas fluorescens 中分离得到的，一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA，并抑制细菌蛋白和RNA 的合成起到抗菌作用。
T0958	Penicillin G sodium salt 青霉素钠,Penicillin G Sodium,Benzylpenicillin sodium salt,Benzylpenicillin Sodium	GABA Receptor; Antibacterial; Antibiotic	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Penicillin G sodium(Benzylpenicillin sodium) salt 是一种 β-内酰胺类抗生素。
T12830	Sapienic acid sodium	Antibacterial	Microbiology/Virology
	Sapienic acid sodium，主要存在于皮肤和粘膜中的脂肪酸，对皮肤和口腔内的革兰氏阳性及阴性细菌展现出不同程度的抗菌效果。其对血链球菌、微生物链球菌与核纤梭菌的抗菌活性表现，MBC值分别为31.3 μg/mL、375.0 μg/mL与93.8 μg/mL。
T20643	Cefoxitin Rephoxitin,Cefoxitinum	Cell wall; Antibacterial; Antibiotic	Immunology/Inflammation; Microbiology/Virology
	Cefoxitin (Rephoxitin) 是一种广谱的、可口服的第二代头孢霉素类抗生素。Cefoxitin 干扰细菌细胞壁的合成。其活性谱包括革兰氏阴性和革兰氏阳性菌，通常用于腹腔感染、盆腔感染和某些类型的妇科感染等腹部，对厌氧菌具有高效性。
T2989	4-Hydroxybenzoic acid p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	4-Hydroxybenzoic acid (4-hydroxybenzoate) 是苯甲酸的酚衍生物，可抑制革兰氏阳性和革兰氏阴性菌，IC50值为160 μg/mL。
T4S0867	Pogostone DHELWANGIN,广藿香酮	Apoptosis; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology
	Pogostone (DHELWANGIN) 是从薄荷中分离出，对革兰氏阴性菌、革兰氏阳性菌、大肠埃希菌等具有强效抗菌、抗真菌活性。它诱导细胞凋亡和自噬。
T4889	2,6-Diaminoheptanedioic acid	Others; Endogenous Metabolite	Metabolism; Others
	2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。
T41078	Lipopolysaccharides, Escherichiacoli (11C) LPS E. coli O55:B5,Lipopolysaccharide, E. coli O111:B4	Others	Others
	Lipopolysaccharides, Escherichiacoli (11C) (LPS E. coli O55:B5)是革兰阴性菌外膜的大分子成分，由脂质a、寡糖核心和o -特异性多糖(O-antigen) 3个区域组成。
T11855	Lipopolysaccharides 脂多糖,LPS	Others	Others
	Lipopolysaccharides (LPS) 属于天然产物，是一种来源于革兰氏阴性菌外膜外叶的内毒素。Lipopolysaccharides 是一种高免疫原性抗原，可以增强免疫反应，可以用于炎症模型构建。
T26805	Bicyclomycin Bicozamycin
	Bicyclomycin is a broad spectrum antibiotic active against Gram-negative bacteria and the Gram-positive bacterium, Micrococcus luteusn.
TN4518	Meridinol	Antifection	Microbiology/Virology
	Meridinol has wide antimicrobial activity, includes against gram-positive and gram-negative bacteria and fungi.
TN6002	Crenatine 1-Ethyl-4-methoxy-β-carboline
	Crenatine possesses antibacterial activity, it is more effective against Gram-positive than Gram-negative bacteria.
T27024	Citromycetin Frequentic Acid,NSC-53584,NSC 53584,NSC53584
	Citromycetin is a fungal metabolite originally isolated from Australian P. frequentans. It has antibiotic activity against the Gram-negative bacteria V. cholerae and S. flexneri and the Gram-positive bacteria S. aureus.
T1255L	Tobramycin Sulfate Dartobcin,Nebcine,Tobraneg,Tobrasix
	Tobramycin Sulfate is a broad-spectrum antibiotic. It is effective against gram-negative bacteria. It especially potent against the Pseudomonas species.
TN1301	6,8-Diprenylgenistein 6,8-二异戊烯基金雀异黄素,鲁冰花	Antifection	Microbiology/Virology
	6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria.
T4131	Arjunic acid	COX; Antifection	Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL.
T16673	Pseudouridimycin PUM	Others	Others
	Pseudouridimycin is a C-nucleoside analogue. Pseudouridimycin is an antibiotic and is a selective bacterial RNA polymerase (RNAP) inhibitor. It is effective against both Gram-negative and Gram-positive bacteria.
TN5930	Ocotillone
	Ocotillone has potent antibacterial activity against Gram-negative bacteria, P. aeruginosa and S. typhimurium, that are without hemolytic activity, whereas it has weak antimicrobial activity against Gram-positive bacteria and fungi. Ocotillone shows only
T32924	Lucidin ethyl ether
	Ibericin 是一种从Prismatomeris filamentosa 根中分离得到的蒽醌代谢产物，对革兰氏阳性菌和革兰氏阴性菌具有一定的抗菌活性。
T38981	D-Tetramannuronic acid
	D-Tetramannuronic acid, an alginate oligomer, is derived from marine brown algae and certain Gram negative bacteria. It serves as a valuable compound for pain and vascular dementia research[4].
T27977	Manzamine A Keramamine A
	Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram negative and gram positive bacteria, an
T40583	N-(3-Oxotetradecanoyl)-DL-homoserine lactone 3-Oxo-C14-AHL,N-(3-Oxotetradecanoyl)-DL-homoserine lactone
	N-(3-Oxotetradecanoyl)-DL-homoserine lactone, part of the N-Acyl homoserine lactone (AHL) family derived from gram-negative bacteria, serves as a quorum sensing (QS) signaling molecule.
T37712	Fumiquinazoline D
	Fumiquinazoline D is a fungal metabolite originally isolated from A. fumigatus that has activity against Gram-positive and Gram-negative bacteria (MICs = 8-16 μg/ml) as well as F. solani and C. albicans fungi (MICs = 32 and 64 μg/ml, respectively).
T8261	Ceftazidime Pentahydrate 头孢他啶五水合物,头孢他啶	Antibacterial; Antibiotic	Microbiology/Virology
	Ceftazidime pentahydrate 是一种β-内酰胺类抗菌剂，对革兰氏阳性和革兰氏阴性需氧细菌有广谱活性，可静脉内或肌肉给药。它对肠杆菌科特别有效，对大多数 β-内酰胺酶具有抗水解作用。
T4984	Cefozopran hydrochloride SCE-2787 hydrochloride	Antifungal	Microbiology/Virology
	Cefozopran hydrochloride (SCE-2787 hydrochloride) 是一种半合成的非肠道头孢菌素。它是一种广谱抗菌抗生素，能抑制大多数革兰氏阴性和革兰氏阳性菌。
T40967	D-Octamannuronic acid
	D-Octamannuronic acid, an alginate oligomer, is derived from marine brown algae and a restricted group of Gram-negative bacteria. It is research-oriented for the study of pain and vascular dementia [4].
T39276	D-Pentamannuronic acid
	D-Pentamannuronic acid is an alginate oligomer, synthesized by marine brown algae and a select group of Gram-negative bacteria. This chemical compound is valuable for research related to pain and vascular dementia[4].
TN1556	Decarine	Antifection	Microbiology/Virology
	Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages.Decarine inhibits fMLP/CB-induced elastase release with IC(50) values < or = 5.53 microg/mL.
T39277	D-Hexamannuronic acid
	D-Hexamannuronic acid, an alginate oligomer, is derived from marine brown algae and a restricted group of Gram negative bacteria. This compound serves as a valuable tool for investigating pain and vascular dementia[4].
TN4264	Isoapetalic acid 胡桐，海棠木	HIV Protease; Antifection	Microbiology/Virology; Proteases/Proteasome
	Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gram-positive bacteria(two Gram-positive bacteria, S. aureus and B. subtilis a
T36532	SCH 38519
	SCH 38519 is an isochromanequinone fungal metabolite originally isolated from Thermomonospora. It inhibits aggregation induced by thrombin , as well as inhibits serotonin secretion in human platelets (IC50s = 68 and 61 μg/ml, respectively). It inhibits the growth of various Gram-negative and Gram-positive bacteria (mean MICs = 122.1 and 0.92 μg/ml, respectively).
T11219	Equisetin	Others	Others
	Equisetin, an N-methylserine-derived acyl tetramic acid isolated from the terrestrial fungus Fusarium equiseti NRRL 5537, functions as a Quorum-sensing inhibitor (QSI) that specifically attenuates QS-regulated virulence phenotypes in P. aeruginosa, presenting a potent lead for treating P. aeruginosa infections without hindering bacterial growth. This tetramate-containing natural product possesses antibiotic and cytotoxic properties, effectively inhibiting the growth of Gram-positive bacteria and...
T40966	D-Heptamannuronic acid
	D-Heptamannuronic acid, an alginate oligomer, is derived from marine brown algae and a select group of Gram-negative bacteria. This compound serves as a valuable research tool in the study of pain and vascular dementia[4].
T37552	(+)-Macrosphelide A
	(+)-Macrosphelide A is a fungal metabolite originally isolated from Microsphaeropsis. It inhibits adhesion of HL-60 human leukemia cells to human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner. It also inhibits the growth of SKOV3 ovarian cancer cells in a concentration-dependent manner. (+)-Macrosphelide A inhibits the growth of Gram-positive bacteria, including B. subtilis, M. luteus, B. thuringiensis, and S. aureus (MICs = 143, 143, 57, and 57 μg/ml, respectivel...
T75753	Magainin 1 TFA
	Magainin 1 TFA (Magainin I TFA) 是从 Xenopus laevis 皮肤中分离出的一种抗菌和两亲性肽。Magainin 1 TFA 对多种革兰氏阴性和革兰氏阳性细菌均表现出抗生素活性。
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天然产物

Cat.No: T2P2937

Target: Others, Antibacterial

EGCG Octaacetate

Cat.No: T8160

Synonym: 乙酰化表没食子儿茶素没食子酸酯,乙酰化EGCG

Target: Others, Antibacterial

Cat.No: TN2011

Synonym: 商陆素-3BETA-芸香糖苷,Ombuin-3beta-rutinoside

Target: Antibacterial

(Z)-2-decenoic acid

Cat.No: TQ0251

Synonym: (Z)-dec-2-enoic acid,(Z)-2-癸烯酸,cis-2-Decenoic acid,cis-dec-2-enoic acid

Target: Others

(+)-Aromadendrene

Cat.No: T8247

Target: Anti-infection

Cat.No: T8062

Synonym: Refosporen,头孢西酮

Target: Others, Antibacterial, Antibiotic

Cat.No: T1306

Synonym: 氟哌酸,MK-0366,诺氟沙星

Target: DNA gyrase, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic

Cat.No: T5037

Synonym: Antibiotic SF-837,Turimycin P3,Medecamycin A1,Rubimycin,麦迪霉素,Platenomycin B1,Espinomycin A

Target: Antibacterial, Antibiotic

Spectinomycin dihydrochloride

Cat.No: T0788

Synonym: 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T1679

Synonym: Thiactin,Bryamycin,Alaninamide,硫链丝菌素

Target: DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T8302

Target: Antibacterial, Antibiotic

Cat.No: T0814L

Synonym: Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,氨苄青霉素,Ampicillin acid

Target: Antibacterial, Antibiotic

Berberine hydrogen sulphate

Cat.No: T5S0814

Synonym: Berberine Bisulfate,硫酸氢黄连素,Umbellatine Sulfate

Target: Antibacterial

D-(+)-Phenyllactic acid

Cat.No: T5274

Synonym: D-3-苯乳酸,D-3-Phenyllactic acid

Target: Endogenous Metabolite, Antibacterial

Fosfomycin sodium

Cat.No: T8262

Synonym: Fosfomycin Disodium,磷霉素钠

Target: Antibacterial, Antibiotic

Mupirocin calcium hydrate

Cat.No: T8148

Synonym: 莫匹罗星钙,Mupirocin calcium

Target: Others, Antibacterial, Antibiotic

Penicillin G sodium salt

Cat.No: T0958

Synonym: 青霉素钠,Penicillin G Sodium,Benzylpenicillin sodium salt,Benzylpenicillin Sodium

Target: GABA Receptor, Antibacterial, Antibiotic

Sapienic acid sodium

Cat.No: T12830

Target: Antibacterial

Cat.No: T20643

Synonym: Rephoxitin,Cefoxitinum

Target: Cell wall, Antibacterial, Antibiotic

4-Hydroxybenzoic acid

Cat.No: T2989

Synonym: p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate

Target: Endogenous Metabolite, Antibacterial

Cat.No: T4S0867

Synonym: DHELWANGIN,广藿香酮

Target: Apoptosis, Antibacterial, Autophagy

2,6-Diaminoheptanedioic acid

Cat.No: T4889

Target: Others, Endogenous Metabolite

Lipopolysaccharides, Escherichiacoli (11C)

Cat.No: T41078

Synonym: LPS E. coli O55:B5,Lipopolysaccharide, E. coli O111:B4

Target: Others

Lipopolysaccharides

Cat.No: T11855

Synonym: 脂多糖,LPS

Target: Others

Cat.No: T26805

Synonym: Bicozamycin

Cat.No: TN4518

Target: Antifection

Cat.No: TN6002

Synonym: 1-Ethyl-4-methoxy-β-carboline

Cat.No: T27024

Synonym: Frequentic Acid,NSC-53584,NSC 53584,NSC53584

Tobramycin Sulfate

Cat.No: T1255L

Synonym: Dartobcin,Nebcine,Tobraneg,Tobrasix

6,8-Diprenylgenistein

Cat.No: TN1301

Synonym: 6,8-二异戊烯基金雀异黄素,鲁冰花

Target: Antifection

Cat.No: T4131

Target: COX, Antifection

Pseudouridimycin

Cat.No: T16673

Synonym: PUM

Target: Others

Cat.No: TN5930

Lucidin ethyl ether

Cat.No: T32924

D-Tetramannuronic acid

Cat.No: T38981

Cat.No: T27977

Synonym: Keramamine A

N-(3-Oxotetradecanoyl)-DL-homoserine lactone

Cat.No: T40583

Synonym: 3-Oxo-C14-AHL,N-(3-Oxotetradecanoyl)-DL-homoserine lactone

Fumiquinazoline D

Cat.No: T37712

Ceftazidime Pentahydrate

Cat.No: T8261

Synonym: 头孢他啶五水合物,头孢他啶

Target: Antibacterial, Antibiotic

Cefozopran hydrochloride

Cat.No: T4984

Synonym: SCE-2787 hydrochloride

Target: Antifungal

D-Octamannuronic acid

Cat.No: T40967

D-Pentamannuronic acid

Cat.No: T39276

Cat.No: TN1556

Target: Antifection

D-Hexamannuronic acid

Cat.No: T39277

Isoapetalic acid

Cat.No: TN4264

Synonym: 胡桐，海棠木

Target: HIV Protease, Antifection

Cat.No: T36532

Cat.No: T11219

Target: Others

D-Heptamannuronic acid

Cat.No: T40966

(+)-Macrosphelide A

Cat.No: T37552

Cat.No: T75753

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